It can be done, but you have to think on it from the other side:
Your game will only be included in such a bundle if it improves the bundle.
This might be just a number of games improvement on bundles that basically "shotgun" small games, but those bundles aren't exactly a way to improve the way people think about your game.
But to be included in a bundle with better games, your game needs to have a minimum quality itself, or the Bundle creator wouldn't want it in its bundle.
And then there are technical requirements - a lot of bundles require your game to be on Steam (or at least greenlight), and that either requires you to pay the greenlight fee yourself, or find a publisher that likes your game enough to handle your game as part of their portfolio (which requires quality again).
Yes, independent DRM-free distribution is possible, but again that has its own requirements...