Or what
@bgillisp said, or you can change the direction the event ("character") is looking at via move route as an instruction or a property from the event itself, that is above the below/same as/above characters window. Opening a door with the knob on the left would have the following move route when the player touches the event: (Player) Turn Up. Now Play an opening door SE. Second move route below that: (This Event, Wait) Turn Left, Wait 3 frames, Turn Right, Wait 3 frames, Turn Up, Through ON. Now Transfer Player and play a closing door SE. A third move route below that: (Player, Skip, Wait) Move Up.
Another way to rotate would be via a Switch: Copy and paste the Event Page, make on the 2nd page the Switch a Condition and have the character on the 2nd page face another direction. Or put a whole other character in its place.