Real talk, medication is for some people but it can be very detrimental for most people right now. I am no professional, but I would highly recommend seeking alternatives for depression. The best thing they can do in the heat of the moment is call a suicide/mental crisis hotline. These are 24/7 and completely free, people volunteer for them and they can be wonderful.
For long term help, they need to get a lot of blood work done. I would recommend first starting with many thyroid tests (it will require more than one for sure, to check many different thyroid hormone levels; I recently had one done checking my T3 and T4, as well as a urine test for a pheochromocytoma). Thyroid problems in 1st world countries are rising extremely fast, especially in each new generation, and many times this causes manic depression and/or anxiety. Another thing to check would be gut health and gut bacteria. These little guys really can control how your mind feels, as health starts in the gut and your natural ability to absorb nutrients and produce hormones. I'm sure most people who have anxiety/depression know a little about serotonin, but most don't realize it's actually mostly produced in your gut by the food you eat. Having a good and healthy diet is crucial for mental health, as well as everything else. And this doesn't just mean "eat less fast food," it means giving up grains, wheat, gluten, all processed foods and discovering what foods you can't tolerate very well. Exercise is very important too, and must be tailored to each individual. And finding hobbies/activities that make you feel like you're fulfilling something can be an amazing cure as well. For me, that's gaming and RPG Maker. Consider things like yoga and meditation. These are all far more effective and healthy than anti-anxiety/depression medicine.
That's not to say medicine isn't great for some people, it is! But it's a very last resort and other more holistic and natural approaches should be tried first, as well as trying to find any abnormalities in the physical side. As stated earlier, therapy is also a great tool. There's absolutely no shame in it. I even use it sometimes!
Best of luck. Be healthy, everyone!