No, they don't. Those things take up almost 2 full tiles, but some of them don't quite fill the tile. Look along the bottom of the shelves - you can see the transparent background. And little slivers at the very top and bottom of the bed.
The repeating pattern on the floor gives it away - if that was an autotile, that pattern would only be around the edges, unless shift-clicking had been used to make it repeat all over.