I use a mix of Sibellius and Music Creator (Cakewalk) for music, beyond my vocaloids,
Sibellius is really exspensive, and a resource eater, but it does a lot, has a large library built in. While you have to mix volume in other software, Sibellius responds to music markings like ppp, pp, p, mp, mf, f, ff, fff, sf<, <, >, and even ds/dc al coda/fine.
Both program allow music creation 'one note input.' Since I'm not a great keyboard player, the manual input leads to less notation errors for me.
I'm not realy a sequencer fan, though the vocaloids are that format.